Molecular-based assays aid diagnosis and treatment decisions
Genomic testing is increasingly impacting prostate cancer diagnosis and treatment, helping clinicians make more informed management decisions based on the specific molecular characteristics of an individual patient’s cancer.
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In this seven-minute video, Eric A. Klein, MD, Chairman of Cleveland Clinic’s Glickman Urological & Kidney Institute, discusses the use of molecular-based tests in determining the appropriateness of active surveillance after diagnosis; in deciding about adjuvant versus salvage therapy following prostatectomy; and in selecting treatment options in metastatic castration-resistant prostate cancer.
Dr. Klein also describes the preliminary evaluation of IsoPSA™, a novel protein structure-based biomarker blood test used to differentiate patients with high-grade (Gleason > 7) prostate cancers from those with low-grade disease. The test was developed by Cleveland Clinic in collaboration with Cleveland Diagnostics, Inc.
The interview with Dr. Klein was conducted by Translational Andrology and Urology and is posted with permission.
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