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Basic & Translational Science

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Identifying Actionable Cancer Mutations

Researchers develop a personalized genomic medicine platform to identify clinically actionable mutations

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Study Reveals Cause of Common Zika Virus Birth Defect

The molecular mechanisms that underlie fetal brain calcification caused by Zika virus infection

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New Frontiers in Epithelial Barrier Research

Researchers identify protector of intestinal barrier

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A Global Hub for State-of-the-Art Pathogen Research

Cleveland Clinic forms Global Center for Pathogen Research & Human Health

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Novel Model Helps Researchers Identify Actionable Drug Target for Ulcerative Colitis

Patient-derived model mirrors the disease’s complexity better than others currently available

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Selective Targeting May Have Therapeutic Potential in TET2-Mutant Neoplasia

TETi76 eliminates TET2-mutant and TET-deficient cancer cells

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Metabolomic Screening Reveals Pre-Existing Signatures in Patients Treated with CAR T-Cell Therapy

Molecular markers could potentially predict major adverse side effects

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Platelet Activation Differs Between Men and Women in Myocardial Infarction and Beyond

Findings in both health and MI highlight need for sex-specific pharmacotherapy research

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