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Basic & Translational Science

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illustration of an alzheimer brain and a packet of sildenafil pills
March 11, 2024/Neurosciences/Research

Sildenafil as an Alzheimer’s Candidate Drug: Further Support From Insurance Database and Mechanistic Studies

Real-world claims data and tissue culture studies set the stage for randomized clinical testing

histology image of a gray matter lesion in a multiple sclerosis brain

Study Suggests Protective Role for Microglia at Borders of Gray Matter Lesions in Progressive MS

Findings challenge dogma that microglia are exclusively destructive regardless of location in brain

photo of grains and niacin supplement pills

Link Discovered Between Excess Niacin and Cardiovascular Disease

Newly identified pathway may explain the so-called niacin paradox

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Multi-Ancestry Genetic Study of Parkinson’s Disease Identifies New Risk Genes in Pursuit of Novel Treatment Targets

International collaboration is most genetically diverse study of the disease to date

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Noninvasive Technology Enhances Ability to Map Brain Activity to Track Behavior Change

Preclinical work promises large-scale data with minimal bias to inform development of clinical tests

Asthma triggers floating around a set of lungs and a person.

Evie's Curated Regular CQD Post 2

Matching SNOMED Term with Curated Post. Please do not touch this post or any of its categories/snomed terms, thank you!

Asthma triggers floating around a set of lungs and a person.

Evie's Curated Regular CQD Post 8

Matching Primary -> Secondary SNOMED Term with Curated Post. Please do not touch this post or any of its categories/snomed terms, thank you!

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Can Boosting Hydrogen Sulfide Bolster Standard-of-Care Glioblastoma Therapy to Extend Survival?

Cleveland Clinic researchers pursue answers on basic science and clinical fronts

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Microglial Immunometabolism Endophenotypes Implicated in Sex Differences in Alzheimer’s Disease

Study suggests sex-specific pathways show potential for sex-specific therapeutic approaches

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