Going to AUA 2017 Annual Meeting? Add These Presentations to Your Itinerary

Cleveland Clinic Glickman Urological & Kidney Institute will have a major presence at American Urological Association’s 2017 Annual Meeting, with more than 80 oral and poster presentations on wide ranging topics in clinical care and best practices, and basic and clinical research. Department of Urology Chair Edmund Sabanegh, MD, and institute Chair Eric Klein, MD, invite colleagues to take note of and attend the following presentations:

1. “Comparative Analysis of High-Throughput Sequencing Platforms for an Oxalate Metabolizing Microbiome: Implications for the Study of the Urologic Microbiome.” (Friday, May 12, 1 p.m.) Anna Zampini, MD, MBA, MS; Aaron Miller, PhD; Manoj Monga, MD. RNA sequencing technologies are shaping understanding of the relationship of the microbiome and nephrolithiasis.
2. “No Stoma, One, or Two? Setting Expectations for Patients with Rectourethral Fistula.” (Saturday, May 13, 7 a.m.) Amanda Chi, MD; Hadley Wood, MD; Kenneth Angermeier, MD. Collaboration means that most rectourethral fistula can be repaired successfully with no stoma, but patients who have undergone secondary procedures are less likely to end up stoma-free.
3. “Robot-Assisted Partial Nephrectomy for Selected Renal Mass Using Off-Clamp Approach Offered Renal Functional Advantage Over On-Clamp.” (Sunday, May 14, 7 a.m.) Pascal Mouracade, MD, MPH, PhD; Jihad Kaouk, MD. In this study, researchers found that RAPN for selected small renal mass using an off-clamp approach offers renal functional advantage over on-clamp, without adding morbidities.
4. “Vascularized Parenchymal Mass Preservation with Partial Nephrectomy: Functional Impact and Predictive Factors.” (Sunday, May 14, 1 p.m.) Jitao Wu, MD; Steven Campbell, MD, PhD. This study suggests that the amount of VPMP, rather than ischemia, may be more important for functional recovery after PN with implications for surgical technique.
5. “Robotic Salvage Pyeloplasty with Buccal Mucosal Onlay Graft – A Simplified Technique.” (Monday, May 15, 3:30 p.m.) Ryan Nelson, DO; Anna Zampini, MD, MBA, MS; Kenneth Angermeier, MD; Georges-Pascal Haber, MD, PhD. This video shows how robotic salvage pyeloplasty with buccal mucosal graft is a potentially more effective approach compared to more extensive and invasive procedures.
6. “Urinary, Bowel, and Sexual Function at Two Years Following Management of Localized Prostate Cancer.” (Tuesday, May 16, 7 a.m.) Shree Agrawal, BS; Eric Klein, MD; Andrew Stephenson, MD. This study looked at factors affecting quality of life after definitive treatment for prostate cancer, and assessed which had the greatest impact.
7. “Sperm Extraction Location Can Affect Early Embryo Morphokinetics.” (Tuesday, May 16, 9:40 a.m.) Edmund Sabanegh, MD; Nina Desai, PhD; Pavinder Gill, MS; Nicholas Tadros, MD. Emerging embryo kinetics technologies suggest that embryo development may be slower in ICSI embryos derived from testicular versus epididymal sperm.

Trends and topics of interest

“AUA is a golden opportunity to gain insight into the most important developments in urology from leaders around the world,” Dr. Sabanegh notes. “Many developments and trends warrant our attention this year, but my Cleveland Clinic colleagues and I believe the following have the most potential for our practices.”

• Molecular diagnostic developments for early stage diagnosis of prostate cancer
  Genomic testing for prostate cancer has revealed important insights into the biology of early-stage disease that can be exploited clinically. These new tools promise to improve patient selection for active surveillance, deciding when to “pull the trigger” in those on surveillance, whom to recommend adjuvant radiation for, and ultimately selection of specific therapies. Eric Klein, MD, Chairman, Glickman Urological & Kidney Institute
• Predictive models for renal function preservation post renal cancer surgery
  Glomerular filtration rate (GFR) loss with renal cancer surgery strongly influences risk of developing chronic kidney disease, but has substantially less impact on survival. In contrast, age and preoperative GFR are much more significant determinants of survival, while GFR loss with surgery, as would be seen with typical partial nephrectomy vs. radical nephrectomy, only changed absolute mortality risk by 1 to 3 percent. Steven Campbell, MD, PhD, Vice-Chairman, Department of Urology
• Association of microbiome and renal calculus risk
  There is a growing appreciation for the impact the gut microbiome plays on the development of human disease. Aaron Miller, PhD, at Cleveland Clinic, is leading this area of research. Advances in the field could improve our understanding of how and why stones form, and may identify novel patient-centered therapeutics aiming at restoring a healthier balance of microflora. Manoj Monga, MD, Director, Center for Endourology and Stone Disease

See you in Boston

“In addition to attending informative oral and poster presentations, being able to share ideas and experiences informally with colleagues from around the world is a tremendously valuable aspect of attending AUA,” Dr. Klein remarks. “Fellowship is another reason to attend AUA, and I look forward to seeing old friends and meeting new colleagues this year in Boston.”

Follow Dr. Klein on Twitter @EricKleinMD and @CleClinicUro, and live-tweet #AUA17 with Cleveland Clinic physicians.