Locations:
Search IconSearch

Dr. Steve Nissen on 3 ESC 2017 Trials That Really Matter (Video)

Beyond the headlines on CANTOS, REVEAL, COMPASS

If you didn’t make it to the European Society of Cardiology (ESC) Congress 2017 the other week, Cleveland Clinic’s Steven Nissen, MD, has got you covered. In the five-minute video below, Dr. Nissen recaps and interprets three important late-breaking trials presented at the meeting:

  • The CANTOS trial of the monoclonal antibody canakinumab and why it represents a turning point in approaches to coronary artery disease
  • The REVEAL trial of the CETP inhibitor anacetrapib and why this agent is unlikely to gain FDA approval despite meeting the study’s primary end point
  • The COMPASS trial and why there’s a price to be paid for giving an antiplatelet drug with an anticoagulant drug in chronic coronary disease

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

As Dr. Nissen puts it in the video: “Three trials, three different domains, three pretty interesting results.”

Advertisement

Related Articles

19-HRT-6507 Vitals-650×450
Rani duplicate post Check Out These Outcomes

A sampling of outcome and volume data from our Heart & Vascular Institute

illustration of the human heart focused on the left atrial appendage
Takeaways From Updated STS Guidelines for Surgical Treatment of Atrial Fibrillation

Concomitant AF ablation and LAA occlusion strongly endorsed during elective heart surgery

illustration of a figure-of-8 stitch for aortic valve repair
Figure-of-8, Hitch-Up Stitch Is Safe and Durable in Bicuspid Aortic Valve Repair

Large retrospective study supports its addition to BAV repair toolbox at expert centers

histology image of lung tissue showing spread through air spaces (STAS)
Lung Cancer Study Links Preoperative Factors With Spread Through Air Spaces

Young age, solid tumor, high uptake on PET and KRAS mutation signal risk, suggest need for lobectomy

x-ray of bone fracture in a forearm
TRAVERSE Substudy Links Testosterone Therapy to Increased Fracture Risk in Older Men With Hypogonadism

Surprise findings argue for caution about testosterone use in men at risk for fracture

echocardiogram showing severe aortic regurgitation
Early Referral for Enlarged Roots Critical to Prevent Residual AR After Aortic Root Replacement With Valve Reimplantation

Residual AR related to severe preoperative AR increases risk of progression, need for reoperation

photo of intubated elderly woman in hospital bed
Proteomic Study Characterizes Markers of Frailty in Cardiovascular Disease and Their Links to Outcomes

Findings support emphasis on markers of frailty related to, but not dependent on, age

3D transesophageal echocardiographic images
New Leaflet Modification Technique Curbs LVOT Obstruction Risk in Valve-in-Valve TMVR

Provides option for patients previously deemed anatomically unsuitable

Ad