Staff to address progress in myriad eye research projects
This year’s Association for Research in Vision and Ophthalmology (ARVO) annual meeting is fast approaching, and Cleveland Clinic Cole Eye Institute researchers are looking forward to sharing their research progress with you.
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If you’re going to Honolulu for ARVO 2018 (April 29-May 3), make room in your itinerary for Cole Eye Institute presentations and poster sessions. See highlights of our nearly 45 presentations below.
In addition, Cole Eye Institute Chair Daniel F. Martin, MD, invites colleagues to meet institute presenters for lively discussions at the institute’s booth (#1103) in the Exhibit Hall. Please review our complete booth schedule.
SUNDAY, APRIL 29
4–4:15 p.m. / Room 312 / Presentation #745
Phase-Decorrelation OCT for Noncontact Measurement of Biomechanical Effects of Corneal Crosslinking
*Brecken Blackburn, Shi Gu, Matthew Ford, Vinicius De Stefano, Michael Jenkins, William Dupps, Andrew Rollins
MONDAY, APRIL 30
12:45–1 p.m. / Room 301AB / Presentation #1550
CDCP1 as a New Regulator for the Development of Pseudomonas aeruginosa Keratitis in Mice
*Lingjun Zhang, Yan Beck, Karthikeyan Bose, Ping Huang, K P Connie Tam, Feng Lin
4:15–4:30 p.m. / Room 315 / Presentation #4967
Modulation of GLUT1 Expression in the RPE Impacts Outer Segment Renewal and Results in Photoreceptor Degeneration
*Aditi Swarup, Ivy Samuels, Jamie Soto, E. Dale Abel, Neal Peachey, Nancy Philp
TUESDAY, MAY 1
12:45–1 p.m. / Room 314 / Presentation #3001
Circadian Clock Gene Bmal1 Governs Kinetics of Retinal Neurogenesis, Lamination and Visual Evoked Responses
*Onkar Sawant, Olivia Zucaro, Rebecca Fuller, Minzhong Yu, Neal Peachey, Sujata Rao
WEDNESDAY, MAY 2
12–12:15 p.m. / Room 316C / Presentation #4469
Discovery of Three Novel Risk Loci for Age-Related Macular Degeneration by Trans-Ethnic Genome-Wide Association Analysis in the VA Million Veteran Program
*Robert Igo, Christopher Halladay, Dana Crawford, Tamer Hadi, Paul Greenberg, Jack Sullivan, Matthew Anger, Steven Fliesler, Scott Damrauer, Wen-Chih Wu, P. Konicki, Neal Peachey, Sudha Iyengar
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THURSDAY, MAY 3
11:45 a.m.–12 p.m. / Room 306AB / Presentation #5957
Visual Sensory Deficits in Amblyopic Children with and without Latent Nystagmus
*Fatema Ghasia, Charles Gallagher
12:30–12:45 p.m. / Room 312 / Presentation# 5981
Analysis of Topography-Guided LASIK Treatment Planning Strategies
*Ronald Krueger, Vinicius De Stefano, Caio Meister
SUNDAY, APRIL 29
1–2:45 p.m. / Poster A0014
Carboxyvinylpyrrole Protein Adducts: Potential AMD Biomarkers
*Geeng-Fu Jang, Jack Crabb, Belinda Willard, Joe Hollyfield, Robert Salomon, John Crabb
3:15–5:15 p.m. / Poster B0214
The Joubert Syndrome Cilia Proteins arl13b, ahi1 and cc2d2a differentially Modify the Severity of Retinal Dysfunction Due to Loss of cep290 in Zebrafish
*Ping Song, Emma Lessieur, Ellen Piccillo, Cabrielle Nivar, Joseph Fogerty, Brian Perkins
3:15–5:15 p.m. / Poster B0225
Lutein and Zeaxanthin Isomers Ameliorate Photoreceptor Degeneration in Pde6rd10 Mice
*Minzhong Yu, Craig Beight
MONDAY, APRIL 30
8:15–10 a.m. / Poster B0163
Differences in Corneal Biomechanical Behavior Between Normal and Keratoconic Corneas Using In-vivo Optical Coherence Elastography
*Vinicius De Stefano, Matthew Ford, Ibrahim Seven, Brent Hughes, William Dupps
8:15–10 a.m. / Poster B0347
Optimizing Case-Control Classification for Age-Related Macular Degeneration in the VA Electronic Health Record Using a Multialgorithm Data Cube Approach
*Sudha Iyengar, Christopher Halladay, Tamer Hadi, Matthew Anger, Xuan-Mai Nguyen, Robert Igo, Paul Greenberg, Dana Crawford, Jack Sullivan, Scott Damrauer, Wen-Chih Wu, Neal Peachey, Eric Konicki
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11:15 a.m.–1 p.m. / Poster C0320
Evaluation of Diabetic Retinopathy Severity and Underlying Panretinal Ischemic Index
*Alice Jiang, Joseph Boss, Sunil Srivastava, Jamie Reese, Justis Ehlers
11:15 a.m.–1 p.m. / Poster C0330
Correlation of Anatomic Features with Panretinal Ischemic Index in Diabetic Retinopathy
*Joseph Boss, Alice Jiang, Sunil Srivastava, Jamie Reese, Justis Ehlers
11:15 a.m.–1 p.m. / Poster C0317
Retinal and Choriocapillaris Evaluation of Diabetic Patients using Optical Coherence Tomography Angiography
*Vivian Qin, Felipe Conti, Sumit Sharma, Aleksandra Rachitskaya, Justis Ehlers, Rishi Singh
3:30–5:15 p.m. / Poster C0062
Association Between Oral Iron Supplementation and Retinal or Subretinal Hemorrhage in the Comparison of Age-Related Macular Degeneration Treatments Trials
*Delu Song, Gui-Shuang Ying, Joshua Dunaief, Rupak Bhuyan, Yafeng Li, Maureen Maguire, Juan Grunwald, Ebenezer Daniel, Stephanie Hagstrom, Daniel Martin
3:30–5:15 p.m. / Poster C0109
Geographic Atrophy: Correlation Between Confocal Scanning Laser Ophthalmoscopy (SLO), Histology and Immunohistology of Retinal Sections in the Region of Expanding Lesions
*Vera Bonilha, Brent Bell, Mary Rayborn, Joe Hollyfield, Stephanie Hagstrom, Gayle Pauer
3:30-5:15 p.m. / Poster# C0140
Expression of Lactate Transporters in the RPE and Photoreceptors is Required for Health and Functional Activity of the Outer Retina
*John Han, Junzo Kinoshita, Brent Bell, Romana Nowak, Nancy Philp, Neal Peachey
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TUESDAY, MAY 1
8:15–10 a.m. / Poster# C0193
Intraoperative Optical Coherence Tomography-Assisted Descemet Membrane Endothelial Keratoplasty in the DISCOVER Study
*Aparna Shah, Jeffrey Goshe, Justis Ehlers
3:30–5:15 p.m. / Poster A0077
Alterations in Optic Nerve Head (ONH) Endoplasmic Reticulum (ER) Stress Response Proteins in Non-Human Primate (NHP) Early Experimental Glaucoma (EG)
*Cheri Stowell, Geeng-Fu Jang, Lei Zhang, Jack Crabb, Juan Reynaud, Stuart Gardiner, Belinda Willard, Nicholas Marsh-Armstrong, John Crabb, Claude Burgoyne
3:30 – 5:15 p.m. / Poster A0214
Anatomic Feature Dynamics and Perfusion Density Following Aflibercept Therapy in Retinal Vascular Disease in the PERMEATE Study
*Natalia Figueiredo, Sunil Srivastava, Rishi Singh, Aleksandra Rachitskaya, Ming Hu, Jamie Reese, Laura Stiegel, Neeley Dukles, Jenna Hach, Leina Lunasco, Carmen Calabrise, Eric Zhou, Justis Ehlers
3:30–5:15 p.m. / Poster B0184
FEVR-like Phenotype of Zone 1 Type 1 Infants Treated with anti-VEGF Therapy
*Christine Sonnie, Jonathan Sears
WEDNESDAY, MAY 2
8:15–10 a.m. / Poster C0074
Impact of Intraoperative OCT Parameters on Anatomic and Visual Outcomes in Primary Macula-Involving Retinal Detachments from the PIONEER Study
*Josep Abraham, Sunil Srivastava, Jamie Reese, Justis Ehlers
11:15 a.m.–1 p.m. / Poster# A0307
Structural and Functional Connectivity of the Optic Radiation in Ultra Low Vision Patients
*Meghan Marino, Alex Yuan, Stephen Jones, Katherine Koenig, Jian Lin, Wanyong Shin, Aleksandra Rachitskaya, Mark Lowe
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THURSDAY, MAY 3
8:15–10 a.m. / Poster A0131
3-Hydroxypyruvate Accumulates in the Retina of Newborn Mice Exposed to Hyperoxia and May Contribute to Angiostasis
*Amit Sharma, Charandeep Singh, Weilin Song, Youstina Bolok, Jin Zhang, George Hoppe, Jonathan Sears
8:15–10 a.m. / Poster A0133
Serine Metabolism is a Key Pathway Involved in the Prevention of Oxygen-Induced Retinopathy by Roxadustat
*Charandeep Singh, Amit Sharma, George Hoppe, Henri Brunengraber, Jonathan Sears
8:15–10 a.m. / Poster A0013
Systemic Reduction of GLUT1 Prevents Hallmarks of Diabetic Retinopathy
*Ivy Samuels, Matthew Tarchick, Timothy Trobenter, Michael Kozlowski
11 a.m.-12:45 p.m. / Poster A0084
Comprehensive Genetic Analysis of the Mir-183/96/182 Cluster Illuminates a Cooperative Function for Support of Hair Cells But Not Retina
*Joseph Fogerty, Lauren Cianciolo, Benjamin Tooke, Brian Perkins
Consult QD is Cleveland Clinic Cole Eye Institute online site to discuss complex cases and its highlight cutting-edge research. Check us out at consultqd.org/oph.
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